Influenza viruses can be divided into three classes, A, B, and C, largely based upon conserved antigenic differences in the internal nucleoprotein. Influenza A virus, typically encountered more frequently than types B and C, and associated with the majority of serious epidemics, can be further subdivided into strains or subtypes based on antigenic differences in the external hemagglutinin proteins (H1-H16) and neuraminidase proteins (N1-N9).
Influenza B virus is predominantly a human pathogen, although it has been found to infect seals. The limited host range of influenza B and a slower rate of mutation than influenza A appears to preclude development of influenza B pandemics, but influenza B is a significant human pathogen and on an individual basis, infection may result in death.
While Influenza A subtype identification is extremely important (vaccine production, epidemiology), the rapid and accurate differentiation of influenza B from influenza A and C and other respiratory agents in humans and animals is also important (treatment and biosecurity). Virusys has developed a highly sensitive and specific enzyme immunoassay for the detection of Influenza B nucleoprotein antigen in complex sample matrices. The assay can be completed in less than 1.5 hr. and contains only one wash step.
See how it compares to other assays here: CVS 2012 Poster-Comparison of 11 FDA Approved RIDTs.pdf
Escherichia coli (or E. coli for short) is a common bacterium that lives in human and animal intestines, where it is present in large numbers. There are hundreds of E. coli strains and most are relatively harmless, causing illnesses such as traveler’s diarrhea only when consumed in exceedingly high numbers. A notorious exception is E. coli strain 0157:H7, an emerging pathogen that produces a powerful toxin and can cause severe illness. E. coli O157:H7 was first recognized as a cause of illness during an outbreak in 1982 traced to contaminated hamburgers. Since seen, incidents were also reported were people became sick after drinking or swimming in water contaminated by E. coli 0157:H7. Symptoms of poisoning by E. coli 0157:H7 include bloody diarrhea, kidney damage, and occasionally death.
For the latest in published research in this area, see Bushon et al - Comparison of immunomagnetic separation/adenosine triphosphate rapid method to traditional culture-based method for E. coli and enterrococci enumeration in wastewater.
The Virusys E. coli IMS Beads have been developed for the immunomagnetic separation (IMS) of E. coli from a wide range of sample matrices.