Question:

Consulting the catalogue available on your Web site, we could be interested by some of your anti-VZV Monoclonal Antibodies (especially, 6A6 VA033-100 and 13B1 VA031-100)

Would you have some experience regarding neutralization assays using these monoclonal antibodies? Have you evaluated their neutralizing activity?

Resolution:

Previous work with neutralization assays using VA030 indicate complement DEPENDANT neutralization and VA032 and VA033 indicate complement INDEPENDANT neutralization.

Antibodies were used at a concentration of 10 µg/ml.

We have NOT done neutralization assays using VA031.